Targeting Calcium Channels to Block Tumor Vascularization
نویسندگان
چکیده
منابع مشابه
Verapamil block of T-type calcium channels.
Verapamil is a prototypical phenylalkylamine (PAA), and it was the first calcium channel blocker to be used clinically. It tonically blocks L-type channels in the inner pore with micromolar affinity, and its affinity increases at depolarized membrane potentials. In T-type calcium channels, verapamil blocks with micromolar affinity and has modestly increased affinity at depolarized potentials. W...
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ژورنال
عنوان ژورنال: Recent Patents on Anti-Cancer Drug Discovery
سال: 2012
ISSN: 1574-8928
DOI: 10.2174/15748928130104